2 Doctors on Longevity & Biohacking
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No genetic test or blood panel predicts your mortality risk more accurately than your body’s maximal oxygen uptake during intense exercise: your VO2max. In a cohort of over 120,000 people, the least fit individuals had roughly five times the mortality risk of the fittest. Mario and Max explain why physical fitness can outweigh excess body weight, how reliable modern wearable estimates are, and why, beyond a certain fitness level, hard intervals become key to increasing your heart’s stroke volume.
Breathe through your nose instead of your mouth? Mario and Max explain how nasal breathing more than doubles the release of nitric oxide, thereby noticeably increasing oxygen saturation in the body. They also explore how nasal strips, mouth taping, and nasal rinses can help with blocked airways.
Take a warm shower in the evening to cool down and fall asleep faster? Mario and Max explain the physiological process behind vasodilation and how a controlled drop in core body temperature can improve sleep efficiency. They also reveal why timing is crucial—and why just ten minutes in the sauna can be enough.
Cold showers in the morning for better focus and fat burning? Mario and Max debunk myths about brown adipose tissue, explain how cold actually affects the nervous system, show how box breathing helps during ice baths, and explain why people who take cold showers get sick less often.
